Millot M., Tomasi S., Studzinska E., Rouaud I. & Boustie J.
(2009):
Cytotoxic constituents of the lichen Diploicia canescens,
Journal of Natural Products,
72: 2177–2180
A new diphenyl ether (1), along with 12 known compounds, was isolated from the lichen Diploicia canescens. The structure of compound 1 was elucidated by spectroscopic data analysis, and the biosynthetic origin of this product is discussed. Secalonic acids B (7), D (8), and F (9) were isolated for the first time from D. canescens. The cytotoxic activities of 1−3, 6−8, and 10 against the B16 murine melanoma and HaCaT human keratinocyte cell lines were evaluated.
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