Uras İ.S., Candido P.H.S., Luís C.M., Marques V., Rodrigues C.M.P., Sobral R.G., Baurmeister A., Konuklugil B. & Gaudêncio S.P.
(2026):
Antarctic marine-derived fungi: Metabolomic signatures and antibiofilm-driven anti-infective potential against drug resistant pathogens,
Marine Drugs,
24(8): 267 [20 p.]
Antarctic marine-derived fungi represent an underexplored reservoir of bioactive secondary metabolites shaped by extreme environmental pressures. In this study, nine fungal isolates obtained from Antarctic macroalgae, lichens, sponge tissue, and sediments were evaluated for their antimicrobial, anticancer, antibiofilm, and metabolomic profiles. Untargeted LC–MS/MS molecular networking (GNPS) revealed a chemically rich metabolome, dominated by alkaloids, followed by polyketides, meroterpenoids, …
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