Krajka‑Kuźniak V., Paluszczak J., Kleszcz R. & Baer‑Dubowska W.
(2021):
(+)‑Usnic acid modulates the Nrf2‑ARE pathway in FaDu hypopharyngeal carcinoma cells,
Molecular and Cellular Biochemistry,
476: 2539–2549
Naturally occurring phytochemicals of different origin and structure, arctigenin, bergenin, usnic acid and xanthohumol,
were shown to affect Nrf2 pathway in the context of various diseases, but their effect on this pathway in cancer cells was not
extensively investigated. This study aimed to evaluate the effect of these compounds on Nrf2 expression and activation in
hypopharyngeal FaDu squamous cell carcinoma cells. FaDu cells were treated with 2 or 10 μM arctigenin, bergenin, (+)-
usnic acid …
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