Galanty A., Popiół J., Paczkowska-Walendowska M., Studzińska-Sroka E., Paśko P., Cielecka-Piontek J., Pękala E. & Podolak I.
(2021):
(+)-Usnic acid as a promising candidate for a safe and stable topical photoprotective agent,
Molecules,
26(17): 5224 [11 p.]
The study aimed to examine whether usnic acid—a lichen compound with UV-absorbing properties—can be considered as a prospective photoprotective agent in cosmetic products. Moreover, a comparison of two usnic acid enantiomers was performed to preselect the more effective compound. To meet this aim, an in vitro model was created, comprising the determination of skin-penetrating properties via skin-PAMPA assay, safety assessment to normal human skin cells (keratinocytes, melanocytes, fibroblasts), …
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