Phan N.-H.-N.., Duong T.-H., Nguyen H.T., Nguyen T.-H.-T., Nguyen N.-H., Vo T.-P.-G., Tran T.-M.-D. & Sichaem J.
(2025):
A new guaiane sesquiterpene from the cultured lichen mycobiont of Diorygma sp.,
Chemistry of Natural Compounds,
61: 297–299
The cultured mycobiont of the Vietnamese crustose lichen Diorygma sp. was subjected to chemical investigation, which led to the isolation and characterization of a new guaiane sesquiterpene, diorygmone F (1), along with three known compounds, pruinosone, β-sitosterol, and methyl 4-hydroxybenzoate. Structural elucidation was achieved through extensive spectroscopic methods, including NMR, HR-ESI-MS, and ECD. Compound 1 displayed modest inhibitory activity against α-glucosidase, with an IC50 value …
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