Dresler S., Hałka-Grysińska A., Baczewska I., Wójciak H., Hawrylak-Nowak B., Kováčik J., Mykhailenko O., Zidorn C., Sagan J. & Hanaka A.
(2025):
Capillary electrophoresis optimization for metabolite separation in Hypogymnia physodes using DoE: Validation across lichen species,
International Journal of Molecular Sciences,
26(10): 4828 [16 p.]
Lichen-specific natural products exhibit a wide range of biological activities, which makes them potentially useful in the pharmaceutical, cosmetic, and nutritional industries. In the present study, a capillary electrophoresis method was developed and optimized for the separation of seven major metabolites, physodic acid, 3-hydroxyphysodic acid, atranorin, physodalic acid, chloroatranorin, salazinic acid, and protocetraric acid, found in Hypogymnia physodes. The optimization was performed using a …
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