Graphis epigraphis is described from Colombia as only the second, genuinely lichenicolous species in the Graphis-Allographa complex in Graphidaceae. It grows on species of Graphis s. str., thus far found on thalli of G. leptoclada and G. pinicola. The new species is characterized by the lirellate ascomata forming delicate, stellately branched patches on the host, the entire, black labia laterally covered by a thin thalline margin formed by the host thallus, the laterally carbonized excipulum, and mostly 5-septate ascospores. The only other lichenicolous species known in this complex, Allographa pauciloculata, differing in its completely carbonized excipulum and partly submuriform ascospores, grows on thalli of A. anomala and is known from Great Britain, whereas G. epigraphis was found in the tropical dry forest region of the Magdalena Valley in Colombia. We performed morphology-based phylogenetic binning to confirm the genus-level placement of both species in Graphis and Allographa, respectively. A comparative survey of lichenicolous Graphidaceae and Gomphillaceae (Graphidales) is given. Keywords: Adelphomyces; Barzalosa; Chroodiscus; Corticifraga; Diploschistes; Girardot; Guabinal; Gyalideopsis; Paragyalideopsis; Taitaia.