The digitization of the lichen herbarium of Natural History Museum of the Grisons revealed various interesting results. The majority of the specimens date from the 19 th century, of which the collections of Gottfried Ludwig Theobald and Eduard Wolfgang Killias are particularly significant. Together with the later finds, including those by Josias Braun-Blanquet, they extensively document the canton of the Grisons. In addition to the species Ochrolechia frigida, which is new to Switzerland, several lichens have been registered as new for the canton. Furthermore, the evidence of numerous Red List species is significant. They provide valuable information for species protection. In addition, the data enable comparisons with the current situation, in particular for the extensively documented Swiss National Park, the region of Chur, and the entire Rhine Valley of Chur including mount Calanda. Keywords: Lichens, Collection, Canton of the Grisons, Natural History Museum of the Grisons, species protection.