Scytinium siskiyouense is endemic to northern California and southwest Oregon, where it grows primarily on hardwoods in mixed midseral Pseudotsuga menziesii/hardwood forest stands. This habitat is moderately widespread but midseral conifer forests are financially lucrative to harvest. Prior to 2015 there were 35 occurrences across its range, 19 of which were in California. Occurrence monitoring following wildfires in 2015 and 2021 showed that these numbers have declined to 29 and 13 (respectively), which represents a 17% decline in occurrences across its range and a 32% decline in California. Wildfire is a significant threat, and is responsible for the decline between 2015 and 2021. Unvisited occurrences within fire perimeters may increase the rate of decline. Eventual canopy closure due to conifer growth can result in death of the substrate tree. Protections in California are limited to a very small number of occurrences, and rely on moderate activity restrictions associated with particular land allocations. Recommended conservation ranks for California are G2G3 S1 and CRPR 1B.1