- Burt S.R., Harper J.K. & Cool L.G.
- Natural Product Research
- 37(13): 2248‒2254
Individuals of Usnea fulvoreagens (Parmeliaceae, lichenised
Ascomycota), a shrubby corticolous species that is widespread in
Europe, East Asia and North America, produce medullary lichen
acids in several distinct chemotypic patterns. One such chemotype
reportedly contains an unidentified substance as the major
secondary metabolite. We isolated this compound from
Californian specimens of U. fulvoreagens and identified it as the
rare depsidone neotricone. A co-occurring compound, conneotricone,
was identified as 4,10-dihydroxy-5-(hydroxymethyl)-8-
11-carboxylic acid by NMR and HPLC-UV-MSn comparison
with the material synthesised from salazinic acid.
Keywords: chemotype; conneotricone; lichen; LC-MS; NMR; perisalazinic acid.
- Saturday, 05 August 2023 17:41