- Author:
- Pham N.-K.-T., Nguyen H.T., Dao T.-B.-N., Vu-Huynh K.L., Nguyen T.-Q.-T., Huynh B.-L.-C., Le T.-D., Nguyen N.-H, Nguyen N.-H. & Duong T.-H.
- Year:
- 2022
- Journal:
- Natural Product Research
- Pages:
- 36(15): 3865–3871
- Url:
- https://doi.org/10.1080/14786419.2021.1892672
Two new phenolic compounds, cristiferides A-B (1-2) together with six known compounds, 2,4-dihydroxyphthalide (3), lecanoric acid (4), orsellinic acid (5), 5-chloroorsellinic acid (6), methyl haematommate (7), and methyl β-orsellinate (8) were isolated from the lichen Parmotrema cristiferum (Taylor) Hale (Parmeliaceae). The structures of isolated compounds were identified from its spectroscopic data and by comparison with the literatures. Compounds 1-3 and 6-8 were evaluated for alpha-glucosidase inhibition. Compounds 2 and 7 revealed potent activity with IC50 values of 72.66 μM and 48.73 μM, respectively.
Keywords: Lichen; Parmotrema cristiferum; cristiferides; depside; Parmeliaceae; monoaromatic compound; alpha-glucosidase.
- Id:
- 34650
- Submitter:
- zdenek
- Post_time:
- Friday, 07 October 2022 15:05
